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. Author manuscript; available in PMC: 2012 Feb 15.
Published in final edited form as: Stroke. 2010 Jul 22;41(9):1946–1950. doi: 10.1161/STROKEAHA.110.587717

TABLE 4.

Cognitive Correlates of Regional (Anterior vs. Posterior) and Total White Matter Hyperintensity Progression

WMH Progression Demographics Added Variable
Cognitive Domain
r2 p β SE r2 p
Anterior .04 0.33 Complex Processing Speed −0.29 .23 .06 .02
Posterior .05 0.24 Visual Construction −0.22 .23 .05 <.05
Total .04 0.30 Complex Processing Speed −0.25 .51 .05 .04

Note. Hierarchical multiple regression analyses consisted of two steps: 1) demographic variables (age, sex and education) were entered as a block, and 2) five cognitive composite difference scores (complex processing speed, working memory, general memory, visual-constructional skills, and language) were entered in a stepwise fashion.