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Corticosterone clearance rates and cross-reaction of glucocorticoid agonists. Adrenalectomized animals each received iv injections of corticosterone (CORT, 400 μg), methylprednisolone (PRED, 2000 μg), and dexamethasone (DEX, 500 μg). Blood samples were assayed for corticosterone-like immunoreactivity. Inset shows the period from 100–250 min on an enlarged scale. Values represent mean ± sem (n = 7).
