Table 1.
Therapeutic effect of zinc sulphate and sodium selenite on the lesion sizes (mm) of localized cutaneous leishmaniasis caused by L. major in BALB/c mice compared to control groups
| Group | No | Lesion Size(mm)Before Intervention X* ±2SD** | Lesion Size(mm) After Intervention X* ±2SD** | direction | P value |
|---|---|---|---|---|---|
| Zinc Sulphate | 11 | 2.8±0.3 | 3.4±0.5 | ↑ | 0.57 |
| Sodium Selenite | 11 | 2.4± 0.3 | 3.4± 0.2 | ↑ | 0.73 |
| Control | 11 | 1.8± 0.4 | 3.4±0.4 | ↑ | – |
*
=mean
**
=standard deviation
The mean lesion sizes, were not decreased significantly before (P=0.57) and 4 weeks (P=0.73) after treatment by a two-way analysis of variance (ANOVA).