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. 2011 Dec;22(12):2203–2212. doi: 10.1681/ASN.2011020202

Figure 1.

Figure 1.

Podocyte-specific ablation of Atp6ap2 inevitably caused renal failure. (A) Kaplan-Meier survival curves showing lethality within 4 weeks of birth in the conditional prorenin receptor-knockout (CKO) group. (B) Biochemical analysis of urine and plasma showing renal failure and severe renal protein wasting in CKO mice on postnatal day (P) 21. Cr, creatinine; TP, total protein; TC, total cholesterol; ns, not significant. The data are the means ± SD (n = 10). **P < 0.001 versus wild-type (WT) control.