Table 3.
Multiple regression model for flow-mediated dilation (per % increase) in nondialyzed CKD patients
| Covariate | Standardized β | Coefficient (95% Confidence Interval) | P Value |
|---|---|---|---|
| Prolactin (ng/ml) | −0.078 | −0.005 (−0.009, −0.001) | 0.01 |
| Age (yr) | −0.013 | −0.001 (−0.007, 0.004) | 0.59 |
| Sex (men) | −0.004 | −0.010 (−0.107, 0.132) | 0.86 |
| Diabetes (presence) | −0.011 | −0.033 (−0.194, 0.125) | 0.66 |
| Cardiovascular disease (presence) | −0.018 | −0.057 (−0.085, 0.082) | 0.47 |
| Mean arterial pressure (mmHg) | −0.022 | −0.005 (−0.017, 0.006) | 0.39 |
| Estimated GFR (ml/min per 1.73 m2) | 0.430 | 0.015 (0.011, 0.020) | <0.001 |
| Proteinuria (g/d) | −0.029 | −0.001 (−0.001, 0.001) | 0.26 |
| C-reactive protein (mg/L) | −0.068 | −0.010 (−0.022, 0.001) | 0.07 |
| Albumin (g/dl) | 0.081 | 0.282 (0.117, 0.457) | 0.002 |
| Hemoglobin (g/dl) | −0.329 | −0.172 (−0.203, −0.142) | <0.001 |
| Ca×PO4 (mg2/dl2) | −0.125 | −0.014 (−0.022, −0.006) | <0.001 |
| Parathyroid hormone (pg/ml) | −0.120 | −0.001 (−0.003, −0.001) | 0.03 |
| Intima media thickness (mm) | −0.154 | −1.261 (−1.864, −0.631) | <0.001 |
Coefficient indicates the estimated average difference in flow-mediated dilation for 1 unit higher value in the predictor value (e.g., 1 mmHg for MAP), whereas the standardized beta indicates the average difference per higher SD in the predictor variable (e.g., 5 mmHg for MAP). Adjusted r2=0.69.