Table 2.
Robust linear regression for systolic and diastolic BPs
| Independent Variable, U[Na+]/[K+] | Systolic BP | Diastolic BP | ||
|---|---|---|---|---|
| Change (95% CI)a | P Value | Change (95% CI)a | P Value | |
| Model 1 | 1.58 (0.93, 2.23) | <0.001 | 1.02 (0.64, 1.40) | <0.001 |
| Model 2 | 1.16 (0.63, 1.70) | <0.001 | 0.84 (0.50, 1.18) | <0.001 |
| Model 3 | 1.36 (0.82, 1.90) | <0.001 | 0.95 (0.95, 1.30) | <0.001 |
Model 1: univariable model. Model 2: multivariable model, adjusted for age, sex, race, diabetes mellitus, smoking, body mass index, total cholesterol, estimated GFR, and urine albumin/creatinine ratio. Model 3: Sensitivity analysis excluding participants receiving treatment with diuretic, angiotensin-converting enzyme inhibitors, and angiotensin receptor blocker medication. U[Na+]/[K+], urinary sodium/potassium ratio; 95% CI, 95% confidence interval.
a
Unit for change in BP is mmHg per each 3-unit increase in U[Na+]/[K+].