Table 4.
Robust linear regression analysis for BP stratified by race
| African American | Non–African American | |||
|---|---|---|---|---|
| Change (95% Confidence Interval)a | P Value | Change (95% Confidence Interval)a | P Value | |
| Systolic BP, U[Na+]/[K+] | ||||
| model 1 | 1.23 (0.30, 2.17) | 0.01 | 1.39 (0.51, 2.26) | 0.002 |
| model 2 | 1.22 (0.42, 2.01) | 0.003 | 1.09 (0.35, 1.82) | 0.004 |
| model 3 | 1.53 (0.71, 2.36) | <0.001 | 1.01 (0.27, 1.75) | 0.008 |
| Diastolic BP, U[Na+]/[K+] | ||||
| model 1 | 0.77 (0.25, 1.29) | 0.004 | 1.11 (0.56, 1.66) | <0.001 |
| model 2 | 0.75 (0.27, 1.23) | 0.002 | 0.91 (0.43, 1.40) | <0.001 |
| model 3 | 1.00 (0.48, 1.52) | <0.001 | 0.81 (0.32, 1.31) | 0.001 |
Model 1: univariable model. Model 2: multivariable model, adjusted for age, sex, race, diabetes mellitus, smoking, body mass index, total cholesterol, estimated GFR, and urine albumin/creatinine ratio. Model 3: sensitivity analysis excluding participants receiving treatment with diuretic, angiotensin-converting enzyme inhibitors, and angiotensin receptor blocker medication. U[Na+]/[K+], urinary sodium/potassium ratio.
a
Unit for change in BP is mmHg per each 3-unit increase in U[Na+]/[K+].