TABLE 3.
Test-retest reliability*
| SCALE | INTRA-CLASS CORRELATION COEFFICIENT | ||
|---|---|---|---|
| TIME 1 | TIME 2 | CHANGE | |
| PANSS positive | 0.755 | 0.855 | - |
| PANSS negative | 0.747 | 0.873 | - |
| PANSS total | 0.884 | 0.898 | - |
| YMRS total | 0.844 | 0.737 | - |
| HAM-D-21 total | 0.816 | 0.759 | - |
| CGI-S-SCA positive | 0.573 | 0.632 | - |
| CGI-S-SCA negative | 0.720 | 0.559 | - |
| CGI-S-SCA depressive | 0.667 | 0.444 | - |
| CGI-S-SCA manic | 0.692 | 0.756 | - |
| CGI-S-SCA overall | 0.888 | 0.517 | - |
| CGI-C-SCA positive | - | - | 0.526 |
| CGI-C-SCA negative | - | - | 0.475 |
| CGI-S-SCA depressive | - | - | 0.514 |
| CGI-C-SCA manic | - | - | 0.634 |
| CGI-C-SCA overall | - | - | 0.576 |
*
Based on two sets of videotaped interviews of a single actor representing two time points rated by 10 randomly selected clinical trial raters from the US, India, and Eastern Europe for a total of 30 raters. First and second ratings by each rater were separated by 2 weeks.
†
p<0.05 for all values
- CGI-S-SCA
Clinical Global Impression of Severity for Schizoaffective Disorder
- HAM-D-21
21-item Hamilton Rating Scale for Depression
- PANSS
Positive and Negative Syndrome Scale
- YMRS
Young Mania Rating Scale