| Izzo et al82001 (pilot) |
T1/2 |
26 |
US-guided RFA(margin of ≥ 5mm) |
Complete coagulative necrosis in 25/26 |
| Singletary et al 12 2002 |
T1 |
30 |
Intraoperative RFA→ excision |
Complete ablation in 87% of patients |
| Burak et al102003 |
Tumor ≤ 2 cm in diameter |
10 |
RFA → surgery (1–3 wk later) |
No residual lesions detected on MRI in 8/9 patients |
| Hayashi et al11 2003 |
Tumor ≤ 3 cm in diameter |
10 |
RFA → surgery (1–2 wk later) |
Complete coagulative necrosis in 19/22 |
| Fornage et al92004 |
Tumor ≤ 2 cm in diameter |
21 |
RFA → surgery |
Complete coagulative necrosis in 20 pts |
| Noguchi et al34 2006 |
T1 |
10 |
RFA → surgery |
No Viable Tumor |
| Earashi et al35 2007 |
T1 |
24 |
RFA → surgery |
No Viable Tumor |
| Manenti et al36 2009 |
Tumor ≤ 2 cm in diameter |
34 |
RFA → surgery (4 wks later) |
Complete coagulative necrosis in 26/25 |
| Wiksel et al37 2010 |
≤1.6cm |
31 |
RFA → surgery |
Complete coagulative necrosis in 33/34 |
