Table 3.
Alcohol dependence, illicit drug dependence and tobacco use diagnoses: comparison of administrative diagnoses against chart notation during the past 12 months prior to and including the index date
| Alcohol Problems, Abuse/Dependence | |||||
|---|---|---|---|---|---|
| Unweighted Estimates, %b (N in fraction) | |||||
| Sample | Agreement | Sensitivity | Specificity | PPV | NPV |
| Suicide Death | 90 (331/368) | 74 (90/121) | 98 (241/247) | 94 (90/96) | 89 (241/272) |
| Control | 90 (327/362) | 54 (28/52) | 96 (299/310) | 72 (28/39) | 93 (299/323) |
| AD New User | 90 (515/571) | 63 (73/116) | 97 (442/455) | 85 (73/86) | 91 (442/485) |
| Combineda | 90 (658/730) | 68 (118/173) | 97 (540/557) | 87 (118/135) | 91 (540/595) |
| Weighted Estimates, %b (95% confidence interval) | |||||
| Suicide Death | 90 (87, 94) | 78 (70, 87) | 97 (95, 100) | 94 (88, 100) | 89 (84, 93) |
| Control | 90 (85, 95) | 55 (34, 75) | 97 (95, 99) | 80 (67, 94) | 91 (86, 96) |
| AD New User | 91 (87, 94) | 59 (46, 73) | 98 (96, 100) | 86 (75, 97) | 91 (88, 95) |
| Combineda | 90 (85, 95) | 55 (35, 75) | 97 (95, 99) | 80 (68, 93) | 91 (86, 96) |
| Illicit Drug Use/Abuse/Dependence | |||||
| Unweighted Estimates, %b (N in fraction) | |||||
| Agreement | Sensitivity | Specificity | PPV | NPV | |
| Suicide Death | 90 (331/368) | 74 (26/35) | 92 (305/333) | 48 (26/54) | 97 (305/314) |
| Control | 96 (348/362) | 58 (11/19) | 98 (337/343) | 65 (11/17) | 98 (337/345) |
| AD New User | 93 (533/571) | 70 (38/54) | 96 (495/517) | 63 (38/60) | 97 (495/511) |
| Combineda | 93 (679/730) | 69 (37/54) | 95 (642/676) | 52 (37/71) | 97 (642/659) |
| Weighted Estimates, %b (95% confidence interval) | |||||
| Suicide Death | 90 (86, 94) | 78 (62, 94) | 92 (88, 95) | 51 (35, 67) | 97 (95 99) |
| Control | 97 (94, 99) | 61 (30, 91) | 99 (97, 100) | 70 (43, 96) | 98 (96, 100) |
| AD New User | 91 (85, 96) | 54 (24, 85) | 95 (92, 98) | 58 (37, 79) | 94 (89, 100) |
| Combineda | 97 (94, 99) | 61 (33, 89) | 99 (97, 100) | 69 (45, 93) | 98 (96, 100) |
| Tobacco Use | |||||
| Unweighted Estimates, %b (N in fraction) | |||||
| Agreement | Sensitivity | Specificity | PPV | NPV | |
| Suicide Death | 73 (267/368) | 42 (70/167) | 98 (197/201) | 95 (70/74) | 67 (197/294) |
| Control | 76 (274/362) | 36 (46/128) | 97 (228/234) | 89 (46/52) | 74 (228/310) |
| AD New User | 74 (424/571) | 40 (95/237) | 99 (329/334) | 95 (95/100) | 70 (329/471) |
| Combineda | 74 (541/730) | 39 (116/295) | 98 (425/435) | 92 (116/126) | 70 (425/604) |
| Weighted Estimates, %b (95% confidence interval) | |||||
| Suicide Death | 70 (64, 76) | 42 (33, 52) | 97 (94, 100) | 94 (87, 100) | 63 (56, 70) |
| Control | 76 (70, 82) | 39 (27, 50) | 98 (96, 100) | 91 (83, 99) | 73 (66, 80) |
| AD New User | 77 (72, 82) | 44 (34, 54) | 99 (97, 100) | 95 (90, 100) | 73 (67, 79) |
| Combineda | 76 (70, 82) | 39 (27, 50) | 98 (96, 100) | 91 (84, 99) | 73 (66, 80) |
Note: For alcohol dependence, kappa values are 0.76 for suicide cases, 0.57 for controls and 0.66 for AD new users. For illicit drug dependence, kappa values are 0.53 for suicide cases, 0.55 for controls and 0.63 for AD new users.
Abbreviation: NA is not available, AD is antidepressant; PPV is positive predictive value of an administrative diagnosis; NPV is the negative predictive value of an administrative diagnosis.
a Combined sample of suicide deaths and controls
b Rounded to a whole number