Table 2.
Comparisons of total length of copy number aberrations (CNA) by clinicopathological factor of breast cancers.
| Clinicopathological factor | Total (N = 28) n (%) |
Mean total length of CNA (bp) |
P-value |
|---|---|---|---|
| Histological subtype | |||
| Papillo-tubular | 13 (46) | 27,487,678 | 0.541) |
| Solid-tubular | 3 (11) | 41,158,092 | |
| Scirrhous | 12 (43) | 61,520,542 | |
| Histological grade | |||
| I | 4 (14) | 49,011,523 | 0.322) |
| II | 12 (43) | 47,158,730 | |
| III | 12 (43) | 32,711,871 | |
| Axillary lymph node metastasis | |||
| Positive | 13 (62) | 30,993,870 | 0.303) |
| Negative | 8 (38) | 59,602,019 | |
| ER status | |||
| Positive | 14 (50) | 53,249,555 | 0.433) |
| Negative | 14 (50) | 30,863,969 | |
| HER2 amplification (FISH) | |||
| Positive | 9 (36) | 28,970,829 | 0.753) |
| Negative | 16 (64) | 37,017,451 | |
| C-MYC amplification (FISH) | |||
| Positive | 11 (48) | 38,698,059 | 0.463) |
| Negative | 12 (52) | 22,102,472 |
1): analysis of variance, 2): Jonckheere-Terpstra trend test, 3): t-test