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Inhibition of IL-6 production by LPS-stimulated thioglycollate-elicited macrophages.
| CN | IC50 (μM) | SE | Structural variation |
|---|---|---|---|
| 1 | 30.3 | 4.9 | PIM2, sn-2 ether, sn-1 ester |
| 2 | 40.2 | 6.1 | PIM2, sn-2 and sn-1 both ester |
| 3 | 22.7 | 1.8 | PIM2, sn-2 amide, sn-1 ester |
| 4 | 28.8 | 3.8 | PIM2, sn-2 ester, sn-1 ether |
| 6 | 42.8 | 5.1 | PGM2, sn-2 ether, sn-1 ester |
| 7 | 12.9 | 3.0 | PGM2, sn-2 and sn-1 both ester |
| 8 | 23.3 | 5.0 | PIM2, sn-2 and sn-1 both ether |
