Table 7. Two-way gene-environment interactions of MDR analysis.

Rank	Model		Training Bal. Acc. (%)	Testing Bal. Acc. (%)	P-value*	P-value#
1	Preterm birth	Dampness	59.09	55.60	0.003	1.000
2	IL4Ra	BMI	58.42	55.26	0.008	1.000
3	Dampness	BMI	58.27	56.88	0.002	0.934
4	Carpet	Dampness	58.04	58.04	0.001	0.701
5	STAT6	Dampness	57.85	57.22	0.001	0.914
6	IL13 (rs20541)	Dampness	57.75	56.41	0.002	0.967
7	IL13 (rs1800925)	Dampness	57.54	57.54	0.001	0.883
8	Preterm birth	BMI	57.49	56.42	0.002	0.966
9	in utero ETS	Dampness	57.40	56.80	0.002	0.947
10	ADRB2 (rs1042714)	Dampness	57.34	57.03	0.001	0.914

^*Two-way gene-environment interactions were validated based on 1000 permutations.

^#Two- or Three-way interactions were validated based on 1000 explicit tests.