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. 2012 Feb 15;7(2):e31288. doi: 10.1371/journal.pone.0031288

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Srividya et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(7a) Schematic representation of chromosomal region containing leu2-k repeats flanking the ADE2 and URA3 genes. (7b) WT (KRY615), rtt103 (KRY650), hpr1 (KRY652), strains containing the ADE2, URA3 genes flanked by leu2-k repeats were plated on SC plates (viability) and SC+FOA plates (recombinants). Recombination between the leu2 repeats leads to loss of ADE2 and URA3 genes. The recombination frequency was determined for three independent segregants and error bars denote SD.