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. 2011 Nov 17;25(3):284–289. doi: 10.1038/ajh.2011.214

Figure 5.

Figure 5

Effects of the complement 3a receptor inhibitor, SB290157, on production of angiotensin II (Ang II) in conditioned medium of vascular smooth muscle cells (VSMCs) from spontaneously hypertensive rats (SHR) and Wistar–Kyoto (WKY) rats. VSMCs (106) were incubated first for 24 h with serum-free DMEM and then for 48 h with 2 ml of fresh serum-free DMEM in the absence or presence of 0.1 µmol/l SB290157. The culture medium was collected and subjected to radioimmunoassay for Ang II. Data are means ± s.e.m. (n = 6). *P < 0.05 between indicated columns. DMEM, Dulbecco's modified Eagle's medium.