. Author manuscript; available in PMC: 2013 Feb 1.

Published in final edited form as: Anal Bioanal Chem. 2012 Jan 5;402(5):1889–1898. doi: 10.1007/s00216-011-5604-0

Table 1. Summary of LOPAC¹²⁸⁰ library screening hits.

Sample ID	Sample Name	IC₅₀ (μM)
Sample ID	Sample Name	1′ Screen¹	HTRF²	AlphaScreen
NCGC00094139-01	nor-Binaltorphimine dihydrochloride	31.6	21.9	12.5
NCGC00094284-01	Pergolide methanesulfonate	15.8	24.8	>100
NCGC00094191-01	NF449 octasodium salt	28.2	31.0	31.5
NCGC00094069-01	LY-53,857 maleate	25.1	38.0	94.7
NCGC00022834-04	Metergoline	25.1	52.0	81.8
NCGC00093637-01	SB 200646 HCl	20.0	55.7	99.2

IC₅₀ calculated from HTRF assay in 5-point 1:5 titration covering a concentration range of 92 nM – 57.5 μM.

IC₅₀ calculated from from HTRF assay in 12-point 1:3 titration covering a concentration range of 0.3 nM – 57.5 μM.

Table 1. Summary of LOPAC1280 library screening hits.