Table 5.
Antifungal activities of EGCG derivatives.
| Organism | EGCG and its derivatives (MIC: μg/ml) |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| C8 × 2 | C16 | C16E | C18 | C18E | C18DE | C18TE | EGCG | Fluconazole | |
| Candida albicans ATCC24433 | 32 | 32 | 16 | 16 | 16 | 16 | 16 | 64 | 0.25 |
| Candida parapsilosis ATCC22019 | 16 | 16 | 16 | 16 | 16 | 16 | 16 | 64 | 2 |
| Candida tropicalis ATCC750 | 32 | 32 | 16 | 32 | 32 | 32 | 16 | 64 | 2 |
| Candida krusei ATCC6258 | 16 | 16 | 16 | 16 | 16 | 16 | 16 | 64 | 32 |
| Candida glabrata ATCC90030 | 16 | 16 | 16 | 16 | 16 | 32 | 32 | 32 | 16 |
| Cryptococcus neoformans ATCC90112 | 16 | 8 | 8 | 16 | 16 | 8 | 8 | 64 | 1 |
| Aspergillus fumigatus* | 32 | 32 | 16 | 32 | 32 | 32 | 16 | 64 | >64 |
*A clinical isolate from Japan.