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. 2011 Dec 27;5:28. doi: 10.3389/fncel.2011.00028

Table 3.

Examples of Arx-bound and regulated genes that are down-regulated in migrating cortical interneurons (IN) compared to neurons in the ganglionic eminences (GE) and cortical non-interneurons (non-IN).

Gene Arx knock-out mice (Quillé et al., 2011) Arx-transfected N2a cells Expression in cortical migrating interneurons
(Quillé et al., 2011) Cells and stage FC Reference
Hmgn3 ↓ KO subpallium (FC = 1.3, p < 0.001) No specific change GE >IN at E15.5 2.1 Faux et al. (2010)
Non-IN > IN at E13.5 2.6-2.9 Batista-Brito et al. (2008)
Lmo1 ↑ KO subpallium (FC = 1.6, p < 0.001/ ↓ N2a cells (p < 0.05) GE > IN at E13.5 and E15.5 3.0–5.3 Faux et al. (2010)
Fulp et al., 2008/Colasante et al., 2009) Non-IN > IN at E13.5 and E15.5 3.3-5.6 Batista-Brito et al. (2008)/ Fulp et al. (2008)
Ebf3 ↓ KO subpallium (FC = 1.6, p < 0.001/Fulp et al., 2008/Colasante et al., 2009) No specific change GE > IN at E13.5 and E15.5 2.0–2.3 Faux et al. (2010)
Non-IN > IN at E13.5 5.5 Batista-Brito et al. (2008)/Fulp et al. (2008)
Rasgef1b ↑ KO subpallium (Fulp et al., 2008/Colasante et al., 2009) No specific change GE > IN at E13.5 3 Faux et al. (2010)
Non-IN > IN at E14.5 NA Fulp et al. (2008)
Slit2 ↑ KO subpallium (FC = 1.4, p < 0.005) No specific change GE > IN at E13.5 and E15.5 2.1–2.2 Faux et al. (2010)
Non-IN > IN at E13.5 3.5 Batista-Brito et al. (2008)

FC, fold change; NA, not available.