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. 2011 Dec 13;31(4):870–882. doi: 10.1038/emboj.2011.449

Figure 4.

Figure 4

Reduction of germline piRNA levels in kumo mutants. (A) Length histogram of sense and antisense small RNAs produced in the kumo mutant and the control ovaries. An ∼65% reduction in the number of 23–29 nt RNAs was observed in the kumo mutant compared with the control. (B) Diagrams showing piRNA mapping following normalization to a bidirectional cluster at 42AB on chromosome 2R and to unidirectional cluster flamenco on chromosome X. piRNA mapping to the plus strand (blue) and minus strand (red) over cluster 42AB is dramatically reduced in the kumo mutant compared with that in the control ovaries. No such significant reduction in piRNA mapping to the plus strand in the flamenco cluster is observed.