Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Synthetic lethality produced by inhibiting the PI3K and MEK signaling pathways. Inhibition of PI3K or MEK signaling individually fails to exert toxicity, whereas inhibiting both pathways kills cancer cells (courtesy of Dr David Gershenson). RTK, receptor tyrosine kinase.
