Figure 1.

Concentration of select oral antiretrovirals in the genital tract of men and women relative to blood. Adapted from references 35–40.

Notes: In general, the nucleoside reverse transcriptase inhibitors seem to concentrate better in the genital tract of men and women than protease inhibitors and non-nucleoside reverse transcriptase inhibitors (the latter two are excluded from this graph). Some more recent data, although there was significant variability between subjects, shows that raltegravir and maraviroc each can achieve significant levels as well.

*Abacavir achieves lower levels in the female genital tract relative to blood (~40%).