Table 2. Number (±SEM) of c-Fos Positively Labeled Nuclei by Groups and Regions Tested.
0.4 mg/kg Nicotine |
Vehicle |
|||||
---|---|---|---|---|---|---|
nicotine-CS | chamber-CS | CS-alone | nicotine-CS | chamber-CS | CS-alone | |
Prefrontal Cortex | ||||||
PrL | 39.63±6.39 | 35.67±8.62 | 36.69±6.42 | 19.58±3.21 | 23.41±4.46 | 23.91±3.24 |
OFC | 106.56±15.92 | 91.81±18.41 | 100.54±9.20 | 78.38±12.60 | 69.25±14.59 | 57.09±14.02 |
Cg2 | 39.00±6.45 | 31.21±8.51 | 25.83±3.67 | 16.00±2.84 | 12.59±3.97 | 15.77±3.04 |
Striatum | ||||||
dmCPu | 39.96±6.32 | 26.54±5.54 | 25.96±3.61 | 8.83±1.17 | 10.57±2.37 | 9.00±2.22 |
dlCPu | 9.50±2.44 | 5.48±1.54 | 3.94±0.86 | 2.10±0.54 | 5.18±2.46 | 2.93±0.64 |
vmCPu | 45.63±6.68 | 31.00±5.94 | 29.81±5.72 | 17.31±2.31 | 17.59±4.16 | 14.25±3.07 |
vlCPu | 9.56±2.32 | 6.90±2.15 | 4.77±1.07 | 3.19±1.08 | 4.89±2.46 | 4.11±1.05 |
AcbC | 41.63±6.12 | 38.48±6.80 | 30.02±4.78 | 21.44±3.33 | 20.55±3.94 | 16.68±2.94 |
AcbSh | 23.31±4.19 | 18.19±4.64 | 17.38±2.86 | 9.77±1.46 | 9.84±1.76 | 10.20±1.78 |
Hippocampus | ||||||
CA1 | 8.31±1.53 | 7.27±1.70 | 9.04±1.66 | 5.35±1.10 | 4.82±1.56 | 7.02±1.63 |
CA2 | 8.77±1.83 | 7.58±1.79 | 7.25±1.47 | 8.15±1.89 | 5.23±1.78 | 6.98±2.07 |
CA3 | 9.08±1.93 | 6.71±1.25 | 6.35±1.48 | 7.21±1.07 | 5.23±1.55 | 7.09±2.52 |
DG | 17.70±5.02 | 15.27±3.03 | 12.68±3.41 | 12.20±3.50 | 8.07±1.96 | 11.26±3.41 |
Amygdala | ||||||
CeM | 12.81±4.03 | 11.46±1.45 | 11.04±3.09 | 7.08±1.49 | 5.11±0.69 | 6.39±1.49 |
BLA | 10.44±2.18 | 13.15±2.48 | 9.13±2.13 | 5.10±1.06 | 4.70±0.59 | 4.70±0.78 |
MeAD | 14.94±2.31 | 15.29±2.41 | 12.33±1.51 | 9.79±1.97 | 10.20±1.47 | 12.30±2.10 |
Other areas | ||||||
VP | 17.05±2.50 | 18.96±4.94 | 12.15±1.27 | 8.63±2.52 | 7.11±1.37 | 6.05±0.96 |
VTA | 26.02±3.55 | 22.04±3.48 | 18.96±2.77 | 18.17±2.45 | 10.91±1.97 | 16.48±3.61 |
SNR | 9.69±1.95 | 6.77±1.46 | 5.50±1.39 | 3.33±1.18 | 6.64±3.00 | 7.36±3.11 |