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Effects of acute NMDA receptor blockade in the DM striatum. Mean trials to criterion (9/10 correct consecutive trials; ±SEM) on a motor response reversal task. Rats were given bilateral infusions of AP5 or PBS 5 min prior to the beginning of reversal learning. *Significantly different from SAL-pretreated, PBS-infused rats (p<0.01). +Significantly different from METH-pretreated, AP5-infused rats (p<0.05).
