Table 1. Striatal DA Tissue Content 3 Weeks after a Neurotoxic Regimen of METH.
Treatment | Striatal DA tissue content |
---|---|
Dorsolateral | |
Saline (n=8) | 314±26 |
METH (n=8) | 98±15a |
Ventromedial | |
Saline (n=8) | 282±26 |
METH (n=8) | 94±26a |
Values are average (±SEM) DA content (ng DA/mg protein) in striatal tissue determined by HPLC-ECD analysis of 1-mm3 tissue punches from the dorsolateral or ventromedial striatum. Values are ng DA/mg protein.
Significantly different from saline (p<0.05).