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. 2012 Jan 6;14(3):288–301. doi: 10.1093/neuonc/nor219

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© The Author(s) 2012. Published by Oxford University Press on behalf of the Society for Neuro-Oncology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

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Fig. 5. — Percentage (mean ± standard error of the mean) of apoptosis (A, C, E, and G) and necrosis (B, D, F, and H) induced by different BoHV-4 based treatments in different glioma cells: GL261 (A and B), F98 (C and D), GLI36 (E and F) and P26 (G and H). The black bar represents the treatment with BoHV-4-A-TK^HSV-1-IRES-dsRed (BoHV-4-TK^HSV1) + GCV and it has been compared to each of the other conditions with t test. In A, B, C, D, E, and G the induced cell death is higher in BoHV-4^TKHSV1 + GCV than in each of the other treatment. In F and H the induced necrosis was significantly lower if compared to the other BoHV-4 groups and significantly higher if compared to the GCV and control groups (***t test, P < .001. The data presented are the means ± standard errors of 3 different experiments).