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. 2011 Nov 15;12(10):855–864. doi: 10.4161/cbt.12.10.18139

Table 1. Common human and rodent cell lines used in breast cancer animal models. Some of their particular features are noted.

  Estrogen receptor Progesterone receptor ErbB2 receptor Particularities References
Human breast cancer cell lines
BT-474
+
+
+
 
21, 116
MCF-7
+
+
-
Cell line most used
21, 116
MDA MB 231
-
-
-
 
21, 116
SKBR3
-
-
+
 
21, 116
T47-D
+
+
-
 
21, 116
Rat mammary tumor cell lines
UHKBR-01
+
+
-
Same Vimentine, Desmine expression levels as T47-D
117
64–24
-
-
-
Low expression of androgen receptor
118
Walker 256
-
+
-
Rare phenotypic feature particularly aggressive
119
RM22 + - NA Established from a mammary carcinoma chemoinduced (MNU) 120