Table 2. Splenocyte proliferation responses in mice immunized with pBudCE4.1, PBB, PBBG, PBBGI or PBS as control.
| Group | Mean stimulation index ± SD. |
|---|---|
| PBBGI |
4.02 ± 0.23*# |
| PBBG |
3.57 ± 0.31*# |
| PBB |
2.68 ± 0.26# |
| pBudCE4.1 |
2.23 ± 0.26# |
| PBS control | 0.87 ± 0.17 |
Splenocyte proliferation assay was performed using ConA 30 d after the last vaccination. Data represent the mean ± SD. Results were statistically significant in PBBGI and PBBG group as compared with PBB group (indicated as *, p < 0.05) and in PBBGI, PBBG, PBB, and pBudCE4.1 group as compared with PBS control group (indicated as #, p < 0.01). Abbreviations: PBBGI, pBudCE4.1-BCR/ABL-GPI-mIL12-treated group; PBBG, pBudCE4.1-BCR/ABL-GPI-treated group; PBB, pBudCE4.1-BCR/ABL-treated group; pBudCE4.1, pBudCE4.1-treated group; PBS control, PBS-treated group.