Figure 1.
NCTD inhibits melanoma cell survival. (A) Inhibitory effects of CTD and NCTD on 1205Lu cells. The cytotoxicity of CTD and NCTD was evaluated using the MTT assay. Three independent experiments were performed. (B–E) Effect of NCTD on 1205Lu, WM115A, Sbcl2 and WM35 cells. The cytotoxicity of NCTD and temozolomide was evaluated using the MTT assay. Melanoma cells were treated for 12 or 24 h in the presence of various concentrations of NCTD or temozolomide as indicated. * Indicates p < 0.05, compared with corresponding temozolomide treated melanoma cells.