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. 2012 Feb 16;8(2):e1002373. doi: 10.1371/journal.pcbi.1002373

Figure 6. Increasing the number of samples for a fixed depth of coverage improves both components characterization and binning precision.

Figure 6

Left: A fixed number of Inline graphic counts were generated from a model defined by uniformly drawn Inline graphic and Inline graphic matrices using Inline graphic. The value of Inline graphic, the number of samples, varied from 1 to 1000, and 100 trials were performed for each value. The highest average precision of Inline graphic estimation is obtained for Inline graphic. Right: A fixed number of 8,192,000 reads of length 400 bp were sampled from different numbers of samples, each consisting of 15 species in uniformly drawn proportions. The smallest average error over all samples was obtained when 32 samples are sequenced. In both plots the error bars give the standard error of the mean.