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. 2012 Feb 16;8(2):e1002483. doi: 10.1371/journal.pgen.1002483

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Deakin et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) A comparison of gene arrangement on the normal devil chromosome 1 to arrangement observed on DFTD chromosomes shows extensive rearrangement, with only one block of genes (KDSR to KCTD1) conserved in gene order between normal chromosome 1 and DFTD. Yellow regions on DFTD chromosomes indicate homology to normal devil chromosome 1. Genes shown in red mapped to only one location in DFTD, whereas the gene in blue mapped to three different locations. (B) Comparison of gene order of devil chromosome 1 with arrangement in wallaby (left) and opossum (right).