Skip to main content
. 2012 Feb 16;8(2):e1002483. doi: 10.1371/journal.pgen.1002483

Table 3. Predicted location of common tumour suppressor genes and oncogenes in the devil genome.

Gene Opossum Chromosome Predicted Devil Chromosome Nearest Mapped Gene Distance from mapped gene (Mb)
BCL2 3 1 KDSR 0.2
MYC 3 1 ENM01188 8
NF2 3 1 OSBP2 2
APC 6 1 REEP5 0.07
MLH1 6 1 WDR48 0.7
PTEN 1 2 MINPP1 0.3
BRCA2 4 3 SPG20 5
RB1 4 3 FREM2 8
MYCL1 4 3 CCKBR 9
RAD50 5 3 KLHL1 2 and 9
BRCA1 2 4 SOST 2
ERBB2 2 4 SOST 6
TP53 2 4 PGBD2 & C17orf101 6 and 10
NF1 2 4 TPST1 4

Predictions of location in the normal devil genome are based homologies revealed by cross-species chromosome painting. Distance of cancer genes from mapped genes is based on the distance in opossum genome assembly. Only those cancer genes located within a 10 Mb interval either side of a mapped gene are listed.