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. 2012 Feb 16;8(2):e1002367. doi: 10.1371/journal.pcbi.1002367

Figure 5. The effect of initial protein concentrations and Gibbs free energy of subunit association on RLP assembly efficiency.

Figure 5

The initial concentration of vp2, [vp2]0, was kept constant at 1 M while the initial concentrations of vp6 and vp7, [vp6]0 and [vp7]0 respectively, varied from 0.1 M to 1000 M. The Gibbs free energies of vp2, vp6 and vp7 subunit association were considered equal (ΔG0vp2,3-mer = ΔG0vp6,13-mer = ΔG0vp7,13-mer). Graph A shows the RLP assembly efficiency for the irreversible model while graphs B to F show the assembly efficiency of the thermodynamic model for ΔG0vp7,13-mer values of −4.08, −2.58, −1.5, −0.75 and −0.408 kcal.mol−1, respectively. The RLP assembly efficiency is defined as the ratio between the mass of intact RLP and the mass of initial proteins.