Table 1. Patients main features.
| Characteristic | Total (N = 51) | NASH (N = 22) | No NASH (N = 29) | P* | OR [95%CI] |
| Age (years) | 42±10 | 45±9 | 41±11 | 0.105 | |
| Male sex (%) | 26 | 32 | 21 | 0.280 | 0.56 [0.16–2.00] |
| BMI (kg/m2) | 45±6 | 45±6 | 46±7 | 0.739 | |
| Waist (cm) | 132±13 | 133±17 | 134±17 | 0.930 | |
| WTH ratio | 0.97±0.10 | 1.01±0.10 | 0.96±0.11 | 0.095 | |
| Diabetes mellitus (%) | 26 | 27 | 24 | 0.525 | 1.18 [0.33–4.18] |
| Insulin resistance (%) | 57 | 79 | 44 | 0.020 | 4.77 [1.23–18.53] |
| HOMA | 3.9±2.3 | 4.7±2.4 | 3.3±2.0 | 0.049 | |
| Hypertension (%) | 39 | 41 | 38 | 0.528 | 1.13 [0.36–3.52] |
| Smoking (%) | 30 | 24 | 34 | 0.311 | 0.59 [0.17–2.10] |
| Sleep apnea (%) | 23 | 23 | 24 | 0.588 | 0.92 [0.25–3.43] |
| Hypertrigliceridaemia (%) | 19 | 25 | 15 | 0.305 | 1.92 [0.44–8.41] |
| Triglycerides (mg/dL) | 119±43 | 127±49 | 112±37 | 0.223 | |
| HDL-cholesterol (mg/dL) | 51±13 | 48±12 | 53±13 | 0.146 | |
| LDL-cholesterol (mg/dL) | 122±36 | 128±30 | 117±40 | 0.293 | |
| Metabolic syndrome (%) | 43 | 59 | 30 | 0.037 | 3.43 [1.15–11.22] |
| AST (IU/L) | 27±20 | 31±29 | 24±9 | 0.272 | |
| ALT (IU/L) | 33±29 | 41±42 | 27±12 | 0.141 | |
| γ-GT (IU/L) | 37±45 | 54±64 | 25±14 | 0.022 | |
| ALP (IU/L) | 74±22 | 73±26 | 71±14 | 0.306 | |
| Total bilirubin (mg/dL) | 0.7±0.4 | 0.6±0.2 | 0.7±0.4 | 0.274 | |
| Adiponectin (ng/mL) | 20.7±6.2 | 21.1±7.7 | 20.4±5.3 | 0.798 | |
| Leptin (ng/mL) | 19.8±7.3 | 19.9±7.3 | 19.7±7.5 | 0.912 | |
| Ghrelin (pg/mL) | 20.8±13.1 | 18.8±13.9 | 21.9±12.8 | 0.481 | |
| NAS score | 2.7±1.6 | 3.2±1.8 | 2.4±1.3 | 0.105 | |
| Steatosis grade | 1.8±0.8 | 1.9±0.8 | 1.7±0.7 | 0.309 | |
| 1 (n) | 21 | 8 | 13 | ||
| 2 (n) | 18 | 7 | 11 | ||
| 3 (n) | 13 | 7 | 5 | ||
| Hepatocelular ballooning (n) | 3 | 2 | 1 | 0.379 | |
| Lobular inflammatory grade | 0.8±0.8 | 1.1±0.9 | 0.6±0.8 | 0.084 | |
| 0 (n) | 23 | 7 | 16 | ||
| 1 (n) | 16 | 8 | 8 | ||
| 2 (n) | 11 | 6 | 5 | ||
| 3 (n) | 1 | 1 | 0 | ||
| Fibrosis stage | 1.4±0.8 | 2.1±0.5 | 0.9±0.3 | <0.001 | |
| 0 (n) | 4 | 0 | 4 | ||
| 1 (n) | 25 | 0 | 25 | ||
| 2 (n) | 20 | 20 | 0 | ||
| 3 (n) | 1 | 1 | 0 | ||
| 4 (n) | 1 | 1 | 0 |
NASH = non alcoholic steatohepatitis, BMI = body mass index, WTH = waist to hip, AST = aspartate aminotransferase, ALT = alanine aminotransferase, γ-GT = γ-glutamyl transpeptidase, ALP = alkaline phosphatase, NAS = NAFLD activity score.
P* = significance level in the comparison between NASH and non NASH.