. 2012 Feb 16;7(2):e29675. doi: 10.1371/journal.pone.0029675

Table 2. Oxidative stress markers, cytokines, and Lp-PLA₂ activity according to menopausal status.

	Premenopausal women (n = 96)			Postmenopausal women (n = 80)			P₀	P₁
Plasma oxidized LDL(U/L)^∮	40.9	±	11.4	56.7	±	23.8	<0.001	0.031
Urinary 8-epi-PGF_2α (pg/mg creatinine)^∮	1079.1	±	281.6	1199.8	±	461.5	0.179	0.400
Serum IL-6 (pg/mL)^∮	1.94	±	1.28	4.53	±	5.27	<0.001	0.005
Serum TNF-α (pg/mL)^∮	5.88	±	7.03	6.64	±	10.6	0.795	0.213
Serum IL-1ß (pg/mL)^∮	0.70	±	1.17	0.77	±	1.53	0.929	0.961
Lp-PLA₂ activity (nmol/mL/min)	28.3	±	9.42	30.6	±	7.77	0.084	0.447
Nonstimulated PBMC
IL-6 (pg/mL)^∮	786.1	±	3107.9	1409.0	±	6504.8	<0.001	0.027
TNF-α (pg/mL)^∮	169.3	±	803.4	626.9	±	2044.3	<0.001	0.008
IL-1ß (pg/mL)^∮	14.4	±	42.4	119.7	±	351.2	<0.001	<0.001
Lp-PLA₂ activity (nmol/mL/min)	2.01	±	0.55	2.11	±	0.61	0.265	0.621

Mean ± SD. Tested by independent t-test or general linear model with the adjustment.

^∮

tested by log-transformed. P₀: unadjusted, P₁: adjusted for age, BMI and alcohol consumption.

Table 2. Oxidative stress markers, cytokines, and Lp-PLA2 activity according to menopausal status.