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. 2012 Feb 16;7(2):e29675. doi: 10.1371/journal.pone.0029675

Table 3. Correlations among oxidative stress markers, cytokines, and Lp-PLA₂ activity in the circulation and in PBMCs according to menopausal status.

	Premenopausal women (n = 96)						Postmenopausal women (n = 80)
	Plasmaox-LDL		Plasma Lp-PLA₂ activity		Nonstimulated PBMC Lp-PLA₂		Plasma ox-LDL		Plasma Lp-PLA₂ activity		Nonstimulated PBMC Lp-PLA₂
	r₀	r₁	r₀	r₁	r₀	r₁	r₀	r₁	r₀	r₁	r₀	r₁
Plasma ox- LDL(U/L)^∮	-	-	0.244^*	0.247^*	0.022	0.006	-	-	0.390^***	0.394^**	0.215	0.154
Serum IL-6 (pg/mL)^∮	0.042	0.051	−0.150	−0.154	−0.020	−0.032	0.171	0.143	0.022	0.016	0.019	−0.017
Serum TNF-α (pg/mL)^∮	−0.037	−0.016	−0.178	−0.202	0.101	0.068	0.090	0.031	−0.022	−0.018	0.030	−0.008
Serum IL-1ß (pg/mL)^∮	−0.018	−0.020	0.042	0.033	0.073	0.042	−0.061	−0.062	−0.050	−0.046	−0.022	−0.048
Lp-PLA₂ activity (nmol/mL/min)	0.244^*	0.247^*	-	-	0.427^***	0.422^***	0.390^***	0.394^**	-	-	0.380^**	0.374^**
Nonstimulated PBMCs
IL-6 (pg/mL)^∮	0.058	0.042	0.326^**	0.318^**	0.363^***	0.353^**	0.230^*	0.222	0.051	0.073	0.127	0.121
TNF-α (pg/mL)^∮	0.106	0.072	0.209^*	0.202	0.205^*	0.198	0.308^**	0.307^**	0.171	0.208	0.032	0.022
IL-1ß (pg/mL)^∮	0.056	0.035	0.277^**	0.269^**	0.272^**	0.255^*	0.304^**	0.301^**	0.220	0.251^*	0.080	0.067
Lp-PLA₂ activity (nmol/mL/min)	0.022	0.006	0.427^***	0.422^***	-	-	0.215	0.154	0.380^**	0.374^**	-	-

Pearson and partial correlation analysis, r₀: unadjusted, r₁: adjusted for age, BMI, and alcohol consumption,

*P<0.05,

**P<0.01,

***P<0.001,

^∮

tested by log-transformed.