Table 5. CAG repeat length of the larger Huntingtin allele in different groups in the COHORT study.
Groups that carry an expanded allele | Groups that do not carry an expanded allele | |||||
Individuals with clinically diagnosed HD[n = 930] | First-degree relatives who pursued genetic testing and carry an expanded allele[n = 248] | First-degree relatives who did not pursue genetic testing and carry an expanded allele[n = 112] | First-degreerelatives who did not pursue genetic testing and do not carry an expanded allele[n = 224] | First-degree relatives who pursued genetic testing and do not carry an expanded allele[n = 41] | Spousesand caregivers[n = 430] | |
(CAG)n of 26 or less [n (%)] | 0 | 0 | 0 | 209 (93.3) | 38 (92.7) | 398 (92.6) |
(CAG)n between 27 and 35 (inclusive) [n (%)] | 0 | 0 | 0 | 15 (6.7) | 3 (7.3) | 32 (7.4) |
(CAG)n between 36 and 39 (inclusive) [n (%)] | 15 (1.6) | 25 (10.1) | 13 (11.6) | 0 | 0 | 0 |
(CAG)n of 40 or more [n (%)] | 915 (98.4) | 223 (89.9) | 99 (88.4) | 0 | 0 | 0 |