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. 2012 Feb 16;7(2):e30708. doi: 10.1371/journal.pone.0030708

Table 1. Outcome measures between BM-MSC treatment groups and control groups.

BM-MSCs HBSS alone Dermalfibroblasts DeadBM-MSCs No treatment Significance (p)
Median day of disease onset (range) 12 (10–16) 12 (10–13) 12 (9–13) 12.5 (10–14) 12 (10–13) 0.76*
Median peak motor score (range) 5.5 (4–7) 5.5 (4–7) 5 (4–6) 5 (4–6) 6 (4–9) 0.3*
Median terminal motor score (range) 3 (0–5) 3 (0–4) 3.5 (2–5) 2 (0–5) 4 (2–6) 0.41*
Mean cumulative motor score (SD) 65.3 (18) 64.3 (17.6) 69.6 (13.3) 64.9 (21.9) 76.9 (12.4) 0.7§
Electrophysiology: ankle-foot median response score (range) 2/1 (0–4)/(0–4) 1/2 (0–3)/(0–4) 1/2 (0–3)/(0–4) 2/2 (0–4)/(0–2) 0/2 (0–2)/(0–3) 0.88*
Mean count of ED1+ cells per HPF (SD) 194 (81) 192 (68) 199 (84) 204 (86) 238 (63) 0.71§
Mean % of myelinated axons per HPF (SD) 25 (27) 27 (20) 27 (22) 31 (24) 9 (5) 0.34§

SD – standard deviation;

*

Kruskal-Wallis test;

§

one way ANOVA, Tukey post-test;

HPF – high power field;