Table 3. Neutralization of HIV-1 Pseudoviruses.
ID50 in TZM-bl1 | ||||||
Group | Rabbit ID | Bleed Week | MN.3 | SF162.LS | Bal.26 | SVA-MLV |
2 | 6869 | 14 | 24 | 258 | – | – |
28 | – | 444 | – | – | ||
3 | 6864 | 6 | 287 | 801 | – | – |
28 | 389 | 960 | 23 | – | ||
3 | 6865 | 6 | – | 136 | – | – |
28 | 45 | 427 | – | – | ||
3 | 6866 | 6 | 338 | 556 | – | – |
28 | 140 | 339 | – | – | ||
5 | 6858 | 6 | – | 532 | – | – |
28 | 23 | 598 | – | – | ||
5 | 6859 | 6 | 25 | 343 | – | – |
28 | 117 | 684 | – | – | ||
5 | 6863 | 6 | 1884 | 3922 | 41 | – |
28 | 763 | 1290 | 35 | – | ||
Pre-bleed | Pool | 0 | – | – | – | – |
Values are the serum dilution at which relative luminescence units (RLUs) were reduced 50% compared to virus control wells (no test sample).
– indicates no neutralization seen at a dilution of 1∶20 (<20).