Figure 3. Effect of Sophora extract on the intestinal and hepatic mRNA levels encoding CYP3A1, CYP3A2, mdr1a and mdr1b.

(A) CYP3A1, (B) CYP3A2, (C) mdr1a, (D) mdr1b. The mRNA contents were measured by real-time PCR and calculated as comparative levels over control using the 2^−ΔΔCT method (mean ± S.E.M., n = 7–9). Statistical significance is indicated as * P<0.05, ** P<0.01, compared to control.