Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Feb 16;7(2):e31960. doi: 10.1371/journal.pone.0031960

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Lacar et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

(A) Z-stack projection of GFAP staining (green, mature and SVZ astrocytes) and PECAM (red, blood vessels) in a horizontal section. The dashed lines encompass the SVZ. LV: lateral ventricle. (B) Texas Red (TR)-Dextran-filled vessels coursing through the SVZ in a live sagittal section. An arteriole (arrow) branches into capillaries. Note the presence of capillary branchpoints (arrowheads). Inset: zoom of the region delineated by the white rectangle in B. The white arrow points to the smooth muscle cells around the arteriole. (C) Z-stack projection of NG2 (green) and PECAM (red) immunofluorescence in a coronal section. NG2 cells on capillaries are pericytes (arrows). (D) Image of the capillary before (control) and during U-46119 (100 nM) application. The capillary was loaded with TR-Dextran through cardiac perfusion prior to slicing. The green arrows indicate the sites of constriction. (E) Mean % change in blood vessel diameters during and after U-46119 applications. Scale bars: 30 (A), 50 (B), 40 (C), and 15 µm (D).