Table 1. Comorbidity associated with chronic diseases.
| EDC | No. Cases | ID only | ID+1 or more | ID+2 or more | ID+3 or more | ID+4 or more | ID+5 or more |
| PATTERN A | |||||||
| Hypertension (with and without complications) [CAR1415] | 28760 | 11.05 | 88.95 | 67.95 | 44.05 | 24.45 | 12.10 |
| Disorders of lipid metabolism [CAR11] | 22345 | 13.19 | 86.81 | 65.76 | 43.29 | 24.58 | 12.49 |
| Type 2 diabetes (with and without complications) [END0607] | 10058 | 9.67 | 90.33 | 74.55 | 54.11 | 33.86 | 18.86 |
| Cardiac arrhythmia [CAR09] | 5777 | 8.60 | 91.40 | 78.43 | 61.28 | 42.08 | 25.36 |
| PATTERN B | |||||||
| Cerebrovascular disease [NUR05] | 2658 | 5.91 | 94.09 | 83.07 | 66.59 | 46.46 | 28.33 |
| Ischemic heart disease (excluding AMI) [CAR03] | 2344 | 3.97 | 96.03 | 86.90 | 70.56 | 49.40 | 32.81 |
| Chronic renal failure [REN01] | 1964 | 5.86 | 94.14 | 84.57 | 69.25 | 51.12 | 33.50 |
| Congestive heart failure [CAR05] | 1377 | 3.05 | 96.95 | 90.12 | 78.29 | 61.26 | 42.19 |
| PATTERN C | |||||||
| Anxiety and depression [PSY0109] | 27357 | 36.46 | 63.54 | 39.54 | 24.38 | 13.91 | 7.14 |
| Thyroid disease [END04] | 19299 | 31.97 | 68.03 | 42.49 | 26.26 | 15.12 | 7.86 |
| Asthma [ALL04] | 7614 | 40.74 | 59.26 | 34.98 | 21.55 | 13.12 | 7.17 |
| Schizophrenia and affective psychoses [PSY07] | 1309 | 31.02 | 68.98 | 44.16 | 24.68 | 13.67 | 7.87 |
| PATTERN D | |||||||
| Obesity [NUT03] | 19640 | 17.11 | 82.89 | 60.58 | 39.76 | 22.68 | 11.36 |
| Osteoporosis [END02] | 6143 | 9.56 | 90.44 | 72.54 | 49.44 | 29.01 | 14.76 |
| Deafness, hearing loss [EAR08] | 5403 | 18.88 | 81.12 | 61.08 | 42.88 | 27.63 | 15.57 |
| Malignant neoplasms [NEOMAL] | 5138 | 14.25 | 85.75 | 66.62 | 46.44 | 28.67 | 15.84 |
| Degenerative joint disease [MUS03] | 4452 | 11.25 | 88.75 | 72.24 | 52.34 | 32.79 | 17.65 |
| Benign prostatic hypertrophy [GUR04] | 4089 | 11.49 | 88.51 | 68.38 | 45.98 | 27.42 | 14.97 |
| Emphysema, chronic bronchitis, COPD [RES04] | 3183 | 9.80 | 90.20 | 72.86 | 54.16 | 35.38 | 21.08 |
| Generalized atherosclerosis [CAR10] | 2705 | 13.20 | 86.80 | 72.16 | 55.75 | 39.26 | 23.51 |
| Glaucoma [EYE08] | 2450 | 7.31 | 92.69 | 79.47 | 60.98 | 40.49 | 23.80 |
| Chronic liver disease [GAS05] | 2121 | 13.11 | 86.89 | 67.61 | 48.33 | 32.81 | 18.39 |
| Dementia and delusions [NUR11] | 1112 | 11.33 | 88.67 | 73.38 | 52.25 | 33.45 | 19.06 |
| Chronic skin ulcer [REC03] | 955 | 8.90 | 91.10 | 77.49 | 58.95 | 41.05 | 24.91 |
| Cardiac valve disease [CAR06] | 936 | 7.69 | 92.31 | 82.16 | 64.10 | 47.54 | 30.02 |
| Parkinson’s disease [NUR06] | 805 | 9.57 | 90.43 | 77.14 | 55.53 | 38.63 | 26.09 |
EDC: expanded diagnosis cluster; ID: index disease; COPD: chronic obstructive pulmonary disease; AMI: acute myocardial infarction.