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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Food Chem Toxicol. 2011 Oct 21;50(2):353–362. doi: 10.1016/j.fct.2011.10.052

Figure 5. Effect of harmaline and harmalol on TCDD-mediated induction of CYP1A1 catalytic activity in HepG2 cells.

Figure 5

Cells were pre-incubated with increasing concentrations of harmaline (A) or harmalol (B) for 30 min before the addition of TCDD (1nM) for an additional 24 h. The amount of CYP1A1 activity was determined using CYP1A1-dependent EROD assay. Resveratrol (Res, 12.5 µM) was used as a positive control. Values represent mean activity ± S.E.M. (n = 8). (+) P < 0.05 compared with control (C), (*) P < 0.05 compared with TCDD (T).