Table 1.

Subject Baseline Characteristics

	Varenicline (n = 493)	Placebo (n = 166)
Overall subjects per site, median (range)	20 (9–43)
Demographic characteristics
Age, years, mean (SD)	43.9 (12.5)	43.2 (12.2)
Men, n (%)	296 (60.0)	99 (59.6)
Race, n (%)
White	335 (68.0)	113 (68.1)
Black	33 (6.7)	8 (4.8)
Asian	103 (20.9)	36 (21.7)
Other	22 (4.5)	9 (5.4)
Body mass index, kg/m2, mean (SD)	26.2 (4.3)	26.7 (4.7)
Smoking history
Years smoked cigarettes, mean (range)	26.0 (2–57)	24.6 (2–59)
Cigarettes/day (past month), mean (range)	21.3 (10–70)	21.5 (10–65)
≥1 previous quit attempt, n (%)	334 (67.7)	106 (63.9)
Longest previous abstinent period in past year, days, mean (range)	4.4 (0–90)	4.7 (0–90)
Fagerström Test for Nicotine Dependence Score, mean (SD)a	5.6 (2.2)	5.4 (2.1)

Note. ^aScores range from 0 to 10, with higher scores indicating greater dependence.