Table 1. Comparison of performance and design feature of furin cleavage site prediction tools.

Prediction tool	Sensitivity	Specificity	Design method	Reference
PiTou	96.9%	97.3%	Biological knowledge-based: combination of a hidden Markov model and biological knowledge- based cumulative probability score functions	Results section
ProP	94.7%	83.7%	Pure machine learning neural network	Duckert et al. 200412