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. 2012 Feb 17;2:274. doi: 10.1038/srep00274

Figure 1. Electron microscopic analysis.

Figure 1

Significant differences in terms of micro-nano structure were observed between HA and HA-Col scaffolds (a–c and b–d respectively). At low magnification, HA foams show round-shaped interconnected pores, with black spots representing interconnections between neighbor pores (a). Ha-Col sponge, on the other side, shows a heterogeneous fibrous structure (b). At higher magnification, HA grains clearly form a substrate for cell adhesion, with black spots representing microporosity (c). Ha-Col scaffold highlights cells grasped to the collagen nanofibers (d). Bars: 200 μm, 500 nm respectively.