Table 2.

Differences of Metabolic and Diffusion Parameters between AAs, OD3s, and OA3s.

Parameter	Percentile	NE Lesion	CE Lesion	CNI2–3	CNI3–4	CNI > 4
nNAA	25th		P = .035 (AA = 0.34, OD3 = 0.19)
LL/NAA	50th (median)	P = .034 (AA = 0.04, OD3 = 0.08)	P = .05 (AA = 0.07, OD3 = 0.20)			P = .012 (AA = 0.08, OD3 = 0.16)
	75th	P = .013 (AA = 0.11, OD3 = 0.17)	P = .022 (AA = 0.14, OD3 = 0.29)	P = .034 (AA = 0.10, OD3 = 0.15)	P = .03 (AA = 0.11, OD3 = 0.20)	P = .018 (AA = 0.15, OD3 = 0.20)
		P = .048 (OD3 = 0.17, OA3 = 0.11)		P = .023 (OD3 = 0.15, OA3 = 0.08)	P = .007 (OD3 = 0.20, OA3 = 0.10)
	90th	P = .023 (AA = 0.18, OD3 = 0.24)	P = .035 (AA = 0.27, OD3 = 0.33)	P = .034 (AA = 0.15, OD3 = 0.21)	P = .015 (AA = 0.16, OD3 = 0.27)
				P = .018 (OD3 = 0.21, OA3 = 0.13)	P = .017 (OD3 = 0.27, OA3 = 0.14)
Lac	50th (median)	P = .036* (OA3 = 3.66, OD3 = 3.50)		P = .03* (AA = 2.18, OD3 = 3.68)

P values were calculated with the Mann-Whitney rank sum test. Only the values that significantly differed between the grade 3 glioma subtypes are reported in this table.

^*There were only three patients with OD3 who had lactate-edited MRSI with visible lactate peaks, and so these differences were not considered significant.