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. Author manuscript; available in PMC: 2012 Feb 17.
Published in final edited form as: Cancer Res. 2010 Oct 15;70(23):9682–9692. doi: 10.1158/0008-5472.CAN-10-2279

Figure 2. S100A4 controls metastatic activity.

Figure 2

(A) LM2 cells were infected with lentiviruses encoding the indicated shRNAs. Equal amounts of total proteins were subjected to immunoblotting with antibodies to the indicated antigens. shSC, non-targeting shRNA; shS100A4, shRNAs targeting S100A4. (B) SN12C cells were infected with retroviruses bearing a vector encoding S100A4 or an empty vector. Total cellular lysis was subjected to immunoblotting using antibodies against the specified proteins. (A, B graphs) Groups of 5 mice were injected in the kidney subcapsule with the indicated cell populations and numbers of lung metastatic nodules were scored after 2 months.