Table 2. A mesenchymal gene signature is upregulated during metastatic conversion of RCC clinical samples.

Comparison of gene expression of primary tumors with matched metastasis from 16 individual RCC patients. Top ranked genes according to SAM analysis and fold change are shown. Genes in blue represent mesenchymal- associated genes.

Gene Name	FC
SFRP2	2.57
COL11A1	1.95
HSPD1	1.93
LOC339047	1.87
OGN	1.86
ITGBL1	1.86
S100A10	1.86
PDZD2	1.78
LOC653786	1.78
PTN	1.74
COL14A1	1.72
COL1A2	1.71
MPPE1	1.70
DCN	1.68
PLCE1	1.66
PPFIBP1	1.66
ASPN	1.65
KIAA1641	1.64
SYNPO2	1.63
PLAGL1	1.62
DLC1	1.62
FBXL21	1.61
SFRP4	1.61