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NAD(P)H oxidase activity (A), representative Western blot analysis and protein content (densitometry) of 12/15-LO (B and C), and 12(S)HETE concentrations (D) in the renal cortex of mice fed a normal or high-fat diet. ND, Mice fed a normal diet; HFD, mice fed a HFD. Mean ± sem, n = 9–13 per group. *, **, P < 0.05 and P < 0.01 vs. group fed normal diet.
