Table 2.
Female reproductive and endocrine phenotype
WT | n | Tacr3+/− | n | Tacr3−/− | n | |
---|---|---|---|---|---|---|
Day of VO | 28.8 ± 0.6 | 20 | 29.9 ± 0.6 | 17 | 29.6 ± 0.9 | 19 |
Day of first estrus | 35.4 ± 1.1 | 10 | 33.9 ± 0.3 | 11 | 34.3 ± 1.2 | 10 |
Uterine weight (% BW) | 0.32 ± 0.03 | 7 | 0.26 ± 0.04 | 7 | 0.06 ± 0.02a | 7 |
Uterine weight (mg) | 68.6 ± 6.4 | 7 | 54.1 ± 7.7 | 7 | 33.4 ± 3.5b | 9 |
Ovarian weight (% BW) | 0.08 ± 0.02 | 5 | 0.06 ± 0.01 | 6 | 0.01 ± 0.13 | 7 |
Ovarian weight (mg) | 13.8 ± 2.1 | 11 | 13.7 ± 1.1 | 12 | 10.2 ± 1.6 | 15 |
LH (ng/ml) | 0.29 ± 0.07 | 12 | 0.25 ± 0.04 | 16 | 0.35 ± 0.07 | 13 |
FSH (ng/ml) | 10.36 ± 1.60 | 8 | 7.38 ± 1.59 | 12 | 7.45 ± 1.29 | 13 |
BW, Body weight.
P < 0.05.
P < 0.001 (ANOVA with Tukey post hoc test).